 | 108 Bocce | Actually it's just 8. Damages nearby enemies. | 12 | 8 | 10 | - Starting weapon of McCoy-Oni
- Ignores Speed, Duration, and Amount
- Scales with Luck or Curse
| Surviving for 15 minutes with McCoy-Oni |
 | Alchemy Whip | Grows stronger every time a boss enemy is defeated. | 10 | 8 | 80 | - Starting weapon of Leon Belmont
- Ignores Speed and Duration
| Surviving 6 minutes with Leon Belmont. |
 | Alucard Spear | Executes a spinning attack when changing horizontal direction. | 10 | 8 | 60 | - Belongs to magic weapons
- Starting weapon of Eric Lecarde
| Inflict a total of 30,000 damage with Alucart Spear. |
 | Alucart Sworb | Allegedly strikes at the nearest enemy. | 5 | 8 | 50 | - Belongs to magic weapons
- Starting weapon of Alucard
| Inflict a total of 10,000 damage with Alucart Sworb. |
 | Arma Dio | Allows you to choose an extra passive weapon. | N/A | 1 | | - Rarity affected by Luck
- Can turn into any normal passive item (rings and metaglios, as well as most DLC passive items cannot be picked).
| Find an Arma Dio in Laborratory |
 | Arrow of Goth | Critical hits maximise amount of projectiles. | 10 | 8 | 20 | - Starting weapon of Alamaric Sniper
- Belongs to magic weapons
- Ignores Duration
| Sold by Master Librarian for 2,800 coins. |
 | Aura Blast | Generates explosive sideways. | 10 | 8 | 20 | - Belongs to magic weapons
- Ignores Speed and Duration
| Sold by Master Librarian for 2,800 coins. |
 | Axe | High damage, high area scaling. | 20 | 8 | 100 | - Starting weapon of Lama Ladonna
- Ignores Duration
- Belongs to vampire-killing tools
| Unlocked by default |
 | Belnades' Spellbook | Allows you to choose from a selection of spells. | N/A | 1 | 2 | - Optional starting weapon of certain eligible characters.
- Juste Belmont may has it as 4th upgrade option until Level 7.
| Evolve all 8 spell lines. |
 | Blade Crossbow | Fires homing projectiles that spin in place when they hit. | 10 | 8 | 50 | - Starting weapon of Sheena Etranzi
- Best with Area and Duration
| Surviving 15 minutes with Sheena |
 | Bone | Throws a bouncing projectile. | 5 | 8 | 1 | - Starting weapon of Mortaccio
- Scales with all stat bonuses
| Unlocking Mortaccio |
 | Bracelet | Fires three projectiles at a random enemy. | 10 | 6 | 40 | - Starting weapon of Gyorunton
- Scales with all stat bonuses
| Survive 30 minutes with either Gallo or Divano |
 | C-U-Laser | Fires a piercing projectile in the faced direction. | 10 | 8 | 50 | - Starting weapon of Lucia Zero
- Best with Duration
| Surviving 15 minutes with Lucia |
 | Candybox | Allows you to choose any unlocked base weapon. | N/A | 1 | 2 | - Starting weapon of Trouser
- Rarity affected by Luck
- Can turn into most unlocked base weapon
| Discover every standard evolution and union |
 | Carréllo | Throws a bouncing projectile. Number of bounces affected by Amount. | 10 | 8 | 1 | - Starting weapon of Bianca Ramba
- Ignores Duration
| Unlocking Bianca Ramba |
 | Celestial Dusting | Throws a bouncing projectile. Cooldown reduces when moving. | 5 | 8 | 1 | - Starting weapon of O'Sole Meeo
- Ignores Speed
- Scales with MoveSpeed
| Unlocking O'Sole |
 | Centralis Custos | Summons Cerberus' vengeful head. Boosts Armor, Recovery and Cooldown when damaged. | 8 | 6 | 70 | - Belongs to ambiguous powers
- Ignores Speed
| Defeat 7,000 enemies with Cornell. |
 | Cherry Bomb | Throws a bouncing projectile that explodes after some time. | 10 | 8 | 1 | - Starting weapon of Yatta Cavallo
- Scales with all stat bonuses and Luck
| Unlocking Cavallo |
 | Clear Debris | Generates projectile spawning zones that follow the player. | 10 | 8 | 50 | - Starting weapon of Guardian Pina
| Reaching level 50 with Guardian Pina |
 | Clock Lancet | Chance to freeze enemies in time. | - | 7 | 70 | - Starting weapon of Iguana Gallo Valletto
- Ignores Might, Speed, Amount, and Area
| Finding an Orologion |